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Journal of Scientific Research and  Studies

Journal of Scientific Research and Studies Vol. 2(2), pp. 56-62, March, 2015

ISSN 2375-8791

Copyright 2015

Author(s) retain the copyright of this article


Full Length Research Paper

The effect of Agaricus blazei Murill on haematological parameter, random blood sugar, total cholesterol, and uric acid of wistar rats (Sprague Dawley)


Misgiati1, 2 and Corebima A.D.2*

1Putra Indonesia Academy of Pharmacy and Food Analysts Malang, Barito 5 Street Malang, Indonesia.
2Department of Biology Education, State University of Malang, Semarang Street Malang, Indonesia.

*Corresponding author. E-mail:

Accepted 4 March, 2015




Agaricus blazei Murill (ABM) has traditionally been used as a prevention and cure of several diseases, such as cancer, diabetes, hypertension, immunostimulant, due to its contents such as 1,3-β-D-Glucan, ergosterol, agaritine, tocoferolum, scorbic acid, terpenes. This study is carried out in order to uncover which doses of ABM powder treatment, classified as suitable doses for a healthy condition of experimental animals based on hematological parameters (haemoglobin, erytrocyt, and leucocyt), random blood sugar, cholesterol, and uric acid. This study was an experimental study using experimental animals (rats) treated with ABM powders (three doses) and pure compounds of 1,3-β-D-Glucan compared to the control group. Based on all parameter studied, it can be concluded that ABM consumption of 7.2 mg is the most suitable one of dose to be recomended for healthy condition.

Key words: Agaricus blazei Murill, hematological parameter, random blood sugar, total cholesterol, uric acid.

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